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Quorum sensing and antibiotic resistance

Quorum sensing and antibiotic resistance

Quorum sensing is a communication pathway found in high-density bacterial colonies, such as in biofilms. Quorum sensing is named after a quorum, the minimum number of people required to hold a meeting or reach a decision. It is so named because it functions by...

Topical Steroid Withdrawal – Fact or Fiction?

Topical Steroid Withdrawal – Fact or Fiction?

Topical Steroid Withdrawal (TSW) has become a sensational topic on the internet and other forms of media. TSW is a side effect of topical corticosteroid use. Topical corticosteroids are used to treat eczema, psoriasis and contact dermatitis.

Biofilms – Is nanomedicine the answer?

Biofilms – Is nanomedicine the answer?

Biofilm is a thin but robust community of bacteria, and sometimes other microorganisms. It is made up of a gel-like material known as extracellular polymeric substances, known as EPS for short.

Unculturable soil bacteria and novel antibiotics

Unculturable soil bacteria and novel antibiotics

Unculturable soil bacteria is a misleading term, as these bacteria hypothetically can be cultured. More accurately, ‘unculturable’ bacteria cannot be cultured using traditional techniques, such as traditional agars. These unknown bacteria are a potential untouched pool of medically useful secondary metabolites, such as antibiotics.

MHRA Green Guide Update 2022

MHRA Green Guide Update 2022

There is a new MHRA Green Guide Update 2022 updated edition of the Rules and Guidance for Pharmaceutical Distributors called the MHRA Green Guide.

Compliance Monitoring Process the MHRA’s new role

Compliance Monitoring Process the MHRA’s new role

Compliance Monitoring Process – from April this year the MHRA are piloting a different approach to the monitoring of companies that are referred to the MHRA’s IAG (Inspection Action Group) for failure to comply with the standards of Good Manufacturing Practice or Good Distribution Practice.

Pharmaceutical Audit Online Training

Pharmaceutical Audit Online Training

The role of the auditor is not only to confirm compliance but is key to the improvement of processes across the company. Whether you work to GDP or ISO standards, it is a requirement that audits are carried out either internally or at the premises of your key suppliers to confirm compliance.